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Knowledge Repository

A complete, user-friendly database of healthcare design research references MoreLess about the Knowledge Repository

The Knowledge Repository is a complete, user-friendly database of healthcare design research references that continues to grow with the latest peer-reviewed publications. Start with our Knowledge Repository for all of your searches for articles and research citations on healthcare design topics. Access full texts through the source link, read key point summaries, or watch slidecasts. Expand your search and find project briefs, interviews, and other relevant resources by visiting our Insights & Solutions page.

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Displaying 1 - 20 of 21

Efficacy of violet–blue light to inactive microbial growth

Author(s): Amodeo, D., Lucarelli, V., De Palma, I., Puccio, A., Nante, N., Cevenini, G., Messina, G.
Research demonstrates that certain lights have antimicrobial properties. Violet-blue light at 405 nm (VBL405) has a broad-spectrum effect on organisms that frequently cause hospital-acquired infections including Clostridium difficile, Escherichia coli, Staphylococcus epidermidis, Pseudomonas aeruginosa, Klebsiella pneumoniae, Streptococcus pyogenes, and various Mycobacterium.
Key Point Summary
Added November 2022

Responsiveness and adaptability of healthcare facilities in emergency scenarios: COVID-19 experience

Author(s): Łukasik, M., Porębska, A.
COVID-19 exposed shortcomings in hospitals’ abilities to accommodate emergency scenarios with efficiency and preparedness. Prior research evaluates strategies for resilient hospitals, such as the use of architectural methods to reduce bacterial infection.
Key Point Summary
Added January 2022

Human factors considerations in designing for infection prevention and control in neonatal care – findings from a pre-design inquiry

Author(s): Trudel, C., Cobb, S., Momtahan, K., Brintnell, J., Mitchell, A.
As healthcare environments are being more frequently redesigned to improve patient experiences and provider operations, it becomes increasingly important that healthcare providers themselves understand how these new designs are intended to be utilized. Giving healthcare providers a deeper understanding of the functions and purposes underlying important healthcare design decisions could help reduce potential operational errors or staff frustrations.
Key Point Summary
Added December 2018

The role of the built environment and private rooms for reducing central line-associated bloodstream infections

Author(s): O’Neill, L., Park, S.-H., Rosinia, F.
Private patient rooms in hospital environments are widely considered a helpful defense against healthcare-associated infections (HAIs). However, the ways in which private rooms might help mitigate specific kinds of HAIs, such as central line-associated bloodstream infections (CLABSIs), remain unclear and relatively unexplored.
Key Point Summary
Added August 2018

Hesitation and error: Does product placement in an emergency department influence hand hygiene performance?

Author(s): Stackelroth, J., Sinnott, M., Shaban, R. Z.
Previous research has thoroughly established the important role proper hand hygiene plays in reducing and controlling healthcare-associated infections (HAIs). Nonetheless, previous studies also show that poor hand hygiene practices remain common in both public and private hospitals. In order to promote effective hand hygiene habits within healthcare environments, designers focus on ensuring that hand hygiene products are easily available and accessible.
Key Point Summary
Added July 2017

Relationship between Environmental Conditions and Nosocomial Infection Rates in Intensive Care Unit

Author(s): Şimşek, E. M., Grassie, S. S., Emre, C., Gevrek, S. Ç.
Due to the highly vulnerable state of the patients populating intensive care units (ICUs) and the health risks posed to healthcare providers working in ICUs, special attention must be given to the causes and effects of nosocomial infections within these areas.
Key Point Summary
Added June 2017

Different Types of Door-Opening Motions as Contributing Factors to Containment Failures in Hospital Isolation Rooms

Author(s): Tang, J. W., Nicolle, A., Pantelic, J., Klettner, C. A., Su, R., Kalliomaki, P., Saarinen, P., Koskela, H., Reijula, K., Mustakallio, P., Cheong, D. K. W., Sekhar, C., Tham, K. W., Costa, C.
When under negative pressure, hospital isolation rooms are essential for both the containment of patients emitting airborne infectious agents as well as the protection of other patients from these agents. A plethora of different doors are used in the construction of these rooms, but relatively few studies have analyzed how certain door-opening motions and the passage of healthcare workers through these doors can affect the overall performance of isolation rooms.
Key Point Summary
Added December 2016

Impact of Neonatal Intensive Care Bed Configuration on Rates of Late-Onset Bacterial Sepsis and Methicillin-Resistant Staphylococcus aureus Colonization

Author(s): Julian, S., Burnham, C.-A., Sellenriek, P., Shannon, W. D., Hamvas, A., Tarr, P. I., Warner, B. B.
Late-onset infections are a continuing issue, causing notable levels of morbidity and mortality in neonatal intensive care units (NICUs), while also increasing the length of patient stay and financial burdens on healthcare institutions. Few previous studies have tested the hypothesis that infants in single-patient rooms have a lower risk of methicillin-resistant Staphylococcus aureus (MRSA) colonization, late-onset sepsis, and death.
Key Point Summary
Added June 2016

Ebola Holding Units at government hospitals in Sierra Leone: evidence for a flexible and effective model for safe isolation, early treatment initiation, hospital safety and health system functioning

Author(s): Johnson, O., Youkee, D., Brown, C. S., Lado, M., Wurie, A., Bash-Taqi, D., Hall, A., Hanciles, E., Kamara, I., Kamara, C., Kamboz, A., Seedat, A., Thomas, S., Kamara, T. B., Leather, A. J. M., Kargbo, B.
The outbreak of Ebola Virus Disease (EVD) in West Africa during 2014-2015 was an unprecedented modern crisis that required novel approaches to outbreak containment and management. In response, the Ministry of Health and Sanitation (MOHS) and the King’s Sierra Leone Partnership (KSLP) in Freetown, Sierra Leone, worked to develop and implement five new Ebola Holding Units (EHUs) in government hospitals, which successfully isolated 37% of the 3,097 confirmed EVD cases within the country’s Western Urban and Rural district.
Key Point Summary
Added June 2016

Development and Use of Mobile Containment Units for the Evaluation and Treatment of Potential Ebola Virus Disease Patients in a United States Hospital

Author(s): Sugalski, G., Murano, T., Fox, A., Rosania, A., Bogucki, S.
University Hospital was in a unique situation for the potential of receiving suspected Ebola patients from Newark (N.J.) International Airport. This situation led to the establishment of an Ebola treatment area (ETA) separate from the main hospital with easy access to hospital employees and equipment when needed. The ETA was built inside a pre-existing building that was empty on the first floor using Western Shelter Systems. This allowed the relatively quick erection of the unit without building a permanent unit.
Key Point Summary
Added June 2016

Impact of sink location on hand hygiene compliance after care of patients with Clostridium difficile infection: a cross-sectional study

Author(s): Deyneko, A., Cordeiro, F., Berlin, L., Ben-David, D., Perna, S., Longtin, Y.
Hand hygiene is typically identified as the most important infection control measure. Many healthcare settings have adopted alcohol-based hand rub solutions because they are extremely easy to use, are accessible, and are effective against microbes. One limitation of alcohol-based hand rubs, however, is their ineffectiveness against spore-forming organisms such as Clostridium difficile infection (CDI). Thus, hand washing in sinks rather than rubbing with solutions is highly recommended after caring for patients with CDI.
Key Point Summary
Added May 2016

Environmental factors and their association with emergency department hand hygiene compliance: an observational study

Author(s): Carter, E. J., Wyer, P., Giglio, J., Jia, H., Nelson, G., Kauari, V. E., Larson, E. L.
Adherence to proper hand hygiene procedures has been repeatedly shown to help prevent healthcare-associated infections (HAIs). Emergency departments (EDs) often experience environmental conditions such as crowding and subsequently end up using non-traditional patient care areas such as hallways to administer treatment. It is possible that the use of non-traditional patient care areas contributes to lower levels of hand hygiene compliance.
Key Point Summary
Added March 2016

The single-patient room in the NICU: maternal and family effects

Author(s): Pineda, R. G., Stransky, K. E., Rogers, C., Duncan, M. H., Smith, G. C., Neil, J., Inder, T.
The authors allude to the references in literature about the stress associated with being the parent of an infant in the Neonatal Intensive Care Unit (NICU). Indicating that the physical environment of a NICU may afford the possibility of alleviating such stress, the authors present the findings of this study which aimed to explore the relationship between the type of NICU room (single-patient versus open bay), parental practices and maternal health.
Key Point Summary
Added July 2015

Measurement of ventilation and airborne infection risk in large naturally ventilated hospital wards

Author(s): Gilkeson, C. A., Camargo-Valero, M. A., Pickin, L. E., Noakes, C. J.
In healthcare environments, the transmission of airborne pathogens is a matter of concern. Ventilation has been identified as one of the key factors in the risk of infection. The authors indicate that most of the evidence on ventilation and infection risk has been in controlled spaces like operating rooms and isolation rooms, and that naturally ventilated spaces like wards have not been studied. They conducted a series of experiments in an unused ward to measure the transmission of pathogens in conditions of natural ventilation, mechanical ventilation, and no ventilation.
Key Point Summary
Added March 2015

HVAC filtration for controlling infectious airborne disease transmission in indoor environments: Predicting risk reductions and operational costs

Author(s): Azimi, P., Stephens, B.
The airborne transmission of infectious pathogens in indoor environments is a matter of concern. The authors refer to different operational and design strategies being used in different buildings to control/limit the spread of these pathogens.
Key Point Summary
Added March 2015

The influence of human walking on the flow and airborne transmission in a six-bed isolation room: Tracer gas simulation

Author(s): Hang, J., Li, Y., Jin, R.
The authors allude to the outbreak of Severe Acute Respiratory Syndrome or SARS and influenza in hospital wards to emphasize the need to protect healthcare workers (HCWs) and non-infected patients. According to the authors, literature indicates that movement of HCWs in hospital wards contributes to the transmission of airborne contaminants. Computational Fluid Dynamics (CFD) was used to simulate the movement of a HCW in an isolation ward and its impact on airborne transmission.
Key Point Summary
Added March 2015

Patient Safety in the Cardiac Operating Room: Human Factors and Teamwork A Scientific Statement From the American Heart Association

Author(s): Wahr, J. A., Prager, R. L., Abernathy, J. H., Martinez, E. A., Salas, E., Seifert, P. C., Groom, R. C., Spiess, B. D., Searles, B. E., Sundt, T. M., Sanchez, J. A., Shappell, S. A., Culig, M. H., Lazzara, E. H., Fitzgerald, D. C., Thourani, V. H., Eghtesady, P., Ikonomidis, J. S., England, M. R., Sellke, F. W., Nussmeier, N. A.
The cardiac surgical operating room is a complex environment, where patient lives are saved or considerably improved with the help of sophisticated equipment and skilled personnel. Although outcomes are improving, adverse events still occur, many of which are preventable. This statement is the result of a review of literature that presented evidence on patient safety and interventions that worked in enhancing patient safety in the cardiac OR.
Key Point Summary
Added March 2015

Assessing the optimal location for alcohol-based hand rub dispensers in a patient room in an intensive care unit

Author(s): Boog, M. C., Erasmus, V., de Graaf, J. M., van Beeck, E. A. H. E., Melles, M, van Beeck, E. F.
The authors allude to literature which says that compliance of hand hygiene (which is crucial to reducing the spread of infectious disease) is low among healthcare workers (HCWs). Literature also shows that alcohol-based hand rubs (ABHRs) improve hand-hygiene compliance by HCWs, which in turn is impacted by location, access to, and visibility of the ABHR dispenser.
Key Point Summary
Added November 2014

Does a mobile laminar airflow screen reduce bacterial contamination in the operating room? A numerical study using computational fluid dynamics technique

Author(s): Sadrizadeh, S., Tammelin, A., Nielsen, P. V., Holmberg, S.
Surgical-site infections (SSIs) can increase patient morbidity and mortality and extend hospitalization time. Operating room (OR) personnel are the main source of airborne bacteria; a person releases roughly 104 skin scales per minute while walking, 10% of which carry bacteria, although up to 12 times as many microorganisms may be discharged depending on the individual and situation. Bacteria in the OR might contaminate a surgical wound through contact with the air or through contaminated surgical instruments.
Key Point Summary
Added November 2014

Reduction of healthcare-associated infections in a long-term care brain injury ward by replacing regular linens with biocidal copper oxide impregnated linens

Author(s): Lazary, A., Weinberg, I., Vatine, J.-J., Jefidoff, A., Bardenstein, R., Borkow, G., Ohana, N.
Due to its antibacterial, antiviral, and fungicidal properties, copper has been widely used for centuries as a biocide. Microorganisms resistant to copper are extremely rare. Recently, methods have been developed for embedding copper oxide particles into textile products, thereby giving them antimicrobial and anti-mite properties, and in some cases, advanced wound-healing abilities. Consumer products featuring copper oxide such as sheets, diapers, and pillowcases have been proven completely safe to humans through numerous studies, with no adverse health reactions on record.
Key Point Summary
Added November 2014