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Knowledge Repository

A complete, user-friendly database of healthcare design research references MoreLess about the Knowledge Repository

The Knowledge Repository is a complete, user-friendly database of healthcare design research references that continues to grow with the latest peer-reviewed publications. Start with our Knowledge Repository for all of your searches for articles and research citations on healthcare design topics. Access full texts through the source link, read key point summaries, or watch slidecasts. Expand your search and find project briefs, interviews, and other relevant resources by visiting our Insights & Solutions page.

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An outbreak of airborne nosocomial varicella

Author(s): Gustafson T. L., Lavely G. B., Brawner Jr., E. R., Hutcheson Jr., R. H., Wright, P. F., Schaffner, W.
An outbreak of nosocomial varicella was traced to airborne spread from an immunocompromised child hospitalized from Nov 11-19, 1980. Seventy potentially susceptible children were hospitalized on the ward during that period. Although the index patient remained in strict room isolation throughout his hospital stay, eight of these patients contracted varicella. The afternoon of November 12 was the...
Key Point Summary
Added August 2012

Efficacy of high-efficiency particulate air filtration in preventing aspergillosis in immunocompromised patients with hematologic malignancies

Author(s): Hahn, T., Cummings, K. M., Michalek, A. M., Lipman, B. J., Segal, B. H., McCarthy Jr., P. L.
Invasive aspergillosis is the most serious type of infections caused by the fungus Aspergillus, affecting organs such as heart, lung, brain, and kidneys and causing symptoms such as chest pain, cough, fever, joint pain, shortness of breath, and unintentional weight loss. The fungus aspergillus is widely spread in the nature and rarely causes problems in healthy individuals.
Key Point Summary
Added August 2012

Nosocomial Transmission of Tuberculosis Associated with a Draining Abscess

Author(s): Hutton, M. D., Stead, W. W., Cauthen, G. M., Bloch, A. B., Ewing, W. M.
Nine secondary cases of tuberculosis and 59 tuberculin skin test conversions occurred after exposure to a hospitalized patient with a large tuberculous abscess of the hip and thigh. Among 442 tuberculin-negative hospital employees, the relative risk of skin test conversion associated with recalled exposure to the patient was 14.0 (95% confidence limits, 6.8, 28.7). Four of 5 surgical suite...
Key Point Summary
Added August 2012

Ventilation of wards and nosocomial outbreak of severe acute respiratory syndrome among healthcare workers

Author(s): Jiang, S. P., Huang, L. W., Chen, X. L., Wang, J. F., Wu, W., Yin, S. M., Chen, W., Zhan, J., Yan, L., Ma, L., Li, J., Huang, Z.
Severe acute respiratory syndrome (SARS) is a contagious respiratory disease caused by a virus called SARS-associated coronavirus. The disease may cause flu-like symptoms including fever (100.4 F or higher), myalgia, lethargy symptoms, cough, and sore throat. Most patients may develop pneumonia. Environmental contamination is an important factor contributing to SRAS transmission.
Key Point Summary
Added August 2012

Microbiological surveillance of hospital ventilation systems in departments at high risk of nosocomial infections

Author(s): Crimi, P., Argellati, F., Macrina, G., Tinteri, C., Copello, L., Rebora, D., Romania, L., Rizzetto, R.
Bacteria exist in large numbers in moist, organic environments and are also found in the air, in water, and on surfaces, particularly in healthcare environments. Patients who are considered high risk are more susceptible to infection by some of these bacteria given the nature of their illness and the treatment they undergo.
Key Point Summary
Added October 2012

Role of ventilation in airborne transmission of infectious agents in the built environment - a multidisciplinary systematic review

Author(s): Li, Y., Leung, G.M., Tang, J.W., Yang, X., Chao, C.Y., Lin, J.Z., Lu, J.W., Nielsen, P.V., Niu, J., Qian, H., Sleigh, A.C., Su, H.J., Sundell, J., Wong, T.W., Yuen, P.L.
The early 2000s saw the surfacing of severe acute respiratory syndrome or SARS, the large-scale return of tuberculosis or TB, an influenza pandemic, and the intentional dispersion of diseases like anthrax – all of which are highly infectious airborne diseases. Authors noted that densely populated urban areas and offices, schools, other buildings, aircraft, and other mass transport vehicles (where people spent most of their time) were ideal for the transmission of SARS.
Key Point Summary
Added October 2012

Hospital Ventilation and Risk for Tuberculous Infection in Canadian Health Care Workers

Author(s): Menzies, D., Fanning, A., Yuan, L., FitzGerald, J.M.
Tuberculosis (TB) is an occupational hazard for healthcare workers. It is a bacterial infection of lungs and other body parts caused by strains of mycobacteria (Mycobacterium tuberculosis). Typical symptoms include chronic cough with bold-tinged sputum, fever, night sweats, and so on. Tuberculosis can cause significant morbidity and death. It is usually spread by air when infected people transmit their saliva through air by coughing and sneezing.
Key Point Summary
Added October 2012

Control of an outbreak of nosocomial aspergillosis by laminar air-flow isolation.

Author(s): Barnes, RA, Rogers, TR
Laminar air flow is a system for circulating filtered air in healthcare facilities. It is very relevant to the issue of Indoor Air Quality and the impact on potential spread of infections. This paper focuses on understanding how using Laminar Air Flow (LAF) can reduce the spread of hospital acquired infections in the context of Bone Marrow Transplant (BMT) patients.
Key Point Summary
Added October 2012

The ventilation of multiple-bed hospital wards: Review and analysis

Author(s): Beggs, C.B., Kevin, G., Noakes, C.J., Hathway, A., Andrewsleigh, P.
Ventilation is a key concern in hospitals, however this has received less attention in the context of hospital wards, as compared to operating theaters or isolation rooms which have a high risk of infections. In many countries in the world where private rooms are not yet the norm, the issue of ventilation in multi-bed rooms is a critical concern. This paper undertakes a review of guidelines in the UK and the US around this issue.
Key Point Summary
Added October 2012

Decreasing Airborne Contamination Levels in High-Risk Hospital Areas Using a Novel Mobile Air-Treatment Unit

Author(s): Bergeron, V., Reboux, G., Poirot, J.L., Laudinet, B.S.
To evaluate the performance of a new mobile air-treatment unit that uses nonthermal-plasma reactors for lowering the airborne bioburden in critical hospital environments and reducing the risk of nosocomial infection due to opportunistic airborne pathogens, such as Aspergillus fumigatus. Tests were conducted in 2 different high-risk hospital areas: an operating room under simulated conditions and...
Key Point Summary
Added October 2012

Impact of Environmental Factors on Efficacy of Upper-Room Air Ultraviolet Germicidal Irradiation for Inactivating Airborne Mycobacteria

Author(s): Xu, P., Kujundzic, E., Peccia, J., Schafer, M., Moss, G., Hernandez, M., Miller, S.
Hospitals are high exposure environments where transmission of infectious diseases is a large concern. To prevent this Ultraviolet Germicidal Irradiation (UVGI) systems are used as an engineering control. A common application is upper-room irradiation for which germicidal lamps are suspended from ceilings/ attached to walls, while the bottom of the lamps are shielded to direct radiation. The principle is to maximize UV radiation exposure to airborne microorganisms in the upper part of the room while minimizing radiation exposure to patients in the lower part.
Key Point Summary
Added October 2012

Effect of ultraviolet germicidal lights installed in office ventilation systems on workers' health and well-being: Double-blind, multiple crossover trial

Author(s): Menzies, D., Popa, J., Hanley, J.A., Rand, T., Milton, D. K.
Most commercial buildings in North America are mechanically ventilated with sealed exterior shells. In this type of highly automatically controlled indoor environment, microbial contamination of the HVAC system often contributes to building-related illness and symptoms in building occupants, such as outbreaks of rhinitis, humidifier fever, asthma, hypersensitivity problems, and so on. Contamination of bacteria, fungi, and protozoa has been found on various parts of HVAC systems such as air cooling units, cooling coils, and drip pans.
Key Point Summary
Added October 2012

Outbreak of Invasive Aspergillus Infection in Surgical Patients, Associated with a Contaminated Air-Handling System

Author(s): Lutz, B. D., Jin, J., Rinaldi, M. G., Wickes, B. L., Huycke, M.
Surgical Site Infections are a prominent concern Operating Room design. In this study a specific outbreak of aspergillus infection in a hospital was investigated and linked back to the air quality conditions in the O.R. The study is significant because typically Aspergillus species are ubiquitous thermotolerant molds that rarely cause invasive infection.
Key Point Summary
Added November 2012

Children’s Experience Regarding the Quality of Their Hospital Stay: The Development of an Assessment Questionnaire for Children

Author(s): Chappuis, M., Vannay-Bouchiche, C.., Fluckiger, M., Monnier, M., Cathieni, F., Terra, R., Piot-Ziegler, C.
Pediatric care quality in Switzerland is evaluated mainly through the parents’ opinion. There are no assessment questionnaires for children. However, research indicates that often, what the parents think does not match their children’s evaluation of the quality of care and that they are often low to moderately correlated. This study examines on the development of a questionnaire assessing the satisfaction of children with their hospital stay.
Key Point Summary
Added December 2013

Effects of low humidity and high air velocity in a heated room on physiological responses and thermal comfort after bathing: An experimental study

Author(s): Hashiguchi, N., Tochihara, T.
Winter often brings low humidity and high air flow from HVAC systems that may cause health-related issues for patients and can impact how comfortable they are before and after a bath.
Key Point Summary
Added January 2014

Unpleasant and pleasant memories of intensive care in adult mechanically ventilated patients—Findings from 250 interviews

Author(s): Samuelson, K. A. M.
Patients’ perspectives on the intensive care experience are essential to improve patients’ comfort and well-being during and after a stay in the intensive care unit (ICU). This research approach was unique as the author used data from a large number of patient interviews (n = 250) and a validated qualitative content analysis technique to create themes from the data. One of the themes included—environmental distress—described aspects of the physical environment that patients remembered as causing distress.
Key Point Summary
Added January 2014

Servicescape: Physical environment of hospital pharmacies and hospital pharmacists’ work outcomes

Author(s): Lin, B.Y.-J., Leu, W.-J., Breen, G.-M., Lin, W.-H.
Researchers have studied the healthcare work environment from a number of angles, from an organizational behavior perspective honing in on motivation and reward, to an occupational and environmental perspective concerned with comfort and ergonomics, to a pathogenic perspective interested in exposure to disease. The idea of a “servicescape” has arisen in healthcare marketing to investigate the impact of the physical environment of service settings on employees’ psychological states and perceptions.
Key Point Summary
Added February 2014

Nurses’ Perceptions of How physical Environment Affects Medication Errors in Acute Care Settings

Author(s): Mahmood, A., Chaudhury, H., Valente, M.
Medication errors in hospitals occur for a number of reasons, stemming from staff and organizational issues to aspects of the physical environment. Errors include omissions, giving the wrong type or amount of medication, and giving the wrong patient unneeded medication. Research has indicated that a significant amount of these errors are avoidable.
Key Point Summary
Added February 2014

Operating Room HVAC Setback Strategies

Author(s): Love, C.
Operating rooms (ORs) have significant HVAC (heating, ventilation, and air conditioning) standards and requirements, yet the rooms tend not to be in use upwards of 40% of the time. As a result, an excessive amount of energy is wasted to maintain air standards for no reason during that period of time. Hospitals have an opportunity to save a significant amount of energy by employing HVAC setback strategies, which minimize the amount of air supplied to the rooms when they are unoccupied. The decision of whether or not to employ a setback strategy for a hospital’s ORs requires an assessment of staff usage, existing conditions, and associated costs.
Key Point Summary
Added March 2014

Medical Gas Cylinder and Bulk Tank Storage

Author(s): McLaughlin, S., Dagenais, D.
There are particular requirements for storing medical gas cylinders as well as requirements for bulk tank storage in healthcare settings; these regulatory requirements exist specifically for cylinders that are not in use. In use refers to cylinders being used by a patient, or attached to equipment and ready for immediate use, or located in patient rooms about to be used. Requirements vary depending on the total amount of cubic feet of gas needing to be stored, with the most stringent regulations for more than 3,000 cubic feet of gas, less stringent requirements for 300-3,000 cubic feet of gas, and the least stringent requirements for less than 300 cubic feet of gas. These requirements are in place to reduce the risk of accident and injury.
Key Point Summary
Added March 2014