Understanding the personal abilities and unique challenges faced by aging individuals, especially those living with Alzheimer’s disease and other dementias, better equips design teams to create supportive living spaces. Devising goals that target single symptoms and objectives is not always practical, however, because changes associated with aging, Alzheimer’s disease, and other dementias tend to appear in “clusters” rather than in isolation. The design-based evidence associated with designing supportive memory care settings results in 12 programmatic design strategies.